About us

Company profile

Genefron, a privately held company, specializes in the development and manufacturing of next generation, in-vitro, personalized and companion diagnostic applications, in autoimmune and acute viral infectious diseases.

The company was  established in 2011 and utilized its first 4 years of intensive R&D to achieve its first proof of concept : predicting the interferon α treatment outcome  in hepatitis C  virus patients.  The prediction accuracy reached 96% in liver biopsies.

Following this achievement Genefron has expanded its success to address chronic autoimmune diseases such as MS and RA. In addition Genefron has developed a PDK used by pregnant to predict CMV transmission to fetus. All PDK are CE marked and Israeli ministry of health approved  (read more ….)

Business Model

In Israel, Genefron is selling its RA kits through marketing company HMO’s covering approximately 70% of the total population. in addition, CMV  transmission predicting tests  are sold through a private certified lab.

Our Pipe Line

Genefron promising pipeline consists current on going clinical trials:

  • PDK for  predicting B cell depletion drugs for RA patients (expected to be on the market at Q3 2018)
  • PDK for predicting anti TNF treatments in psoriasis arthritis and  ankylosing spondylitis.
  • In addition, Genefron is developing new signatures \ products in various stages in inflammatory bowel diseases  as well as local viral disease.

The Leading Team

Mr. Yaniv Kotler (LLB, M.Sc.)
CEO & Founder
Experience:  Biotech entrepreneur, founder and president of a USDA approved aquaculture vaccine company – Kovax Ltd. Serving in various executive roles for 25 years.

Dr. Yoav Smith (Ph.D.)
Genomic data analysis unit Management, Hebrew University – Jerusalem
Experience:  Specializing in genomic analysis, machine learning algorithms, big data analysis and bioinformatics.  Specialized in analysis of various types of biological and clinical data using advanced computing tools .

Dr. Shlomo Pundak (PhD)
Project Manager
Experience: Analytics, drugs, medical device development and  in IVD development and regulation. More than 35 years’ experience in the biotech industry in various leading companies.

Dr. Moshe Abramov (MD)
Scientific adviser & partner Experience:
More than 40 years Specialist gynecologist, Hospital administrator, Meuhedet HMO special adviser for life quality and aging, board chairman and director in biomed and diagnostic companies  and investor in start-up companies

Intellectual Property

The company has a firm IP which includes 1 granted (USA), 4 PCT, 1 provisional, jointly owned with Hebrew University, Israel